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Suboxone Causes Tooth Decay & Other Side Effects: Why Should You Be Careful?

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Suboxone can be best defined as a buprenorphine medication that is used for treating OUD (opioid use disorder). After it received exclusive market access and FDA approval in 2002, the drug manufacturer Indivior.Inc. started to dominate the MAT (medication-assisted-treatment) market.

They quickly came up with multiple forms of this medicine to monopolize the increasing demand and stay ahead of the competition.

The FDA in 2022 issued a safety communication concerning dental issues, such as oral infections, tooth decay, and loss of teeth, in people who used Suboxone Sublingual Film. The plaintiffs, who were harmed by Suboxone, started to file lawsuits against Indivior.

Based on the Suboxone lawsuits filed to date, the sublingual formula of the medicine is highly acidic. It can lead to dental issues like tooth erosion, loss, and decay. That aside, the drug manufacturer had also failed to inform patients or the medical community about these side effects, which could have helped plaintiffs suffer less or not at all.

In this article, we will discuss the lawsuits linked with Suboxone, its side effects, and why you should be aware of them.

The Growing Number of Lawsuits

According to a February 2024 news article in Drugwatch, there haven’t been court-sanctioned settlements declared for Suboxone lawsuits associated with dental issues. No trials have been fixed either.

Additionally, the U.S. Judicial Panel on MDL decided to combine over a dozen Suboxone lawsuits in the Northern District of Ohio. There is also one pending antitrust MDL linked to Suboxone.

Most people have filed a Suboxone tooth decay lawsuit because of severe dental health issues after using the medicine. The lawsuits state that Indivior either should have known or already knew about the side effects and failed to alert consumers and medical providers about it.

Severe dental problems are associated with Suboxone, which is a strip that dissolves in the user’s mouth. Even though it appears and functions similarly to breathe-freshening strips, the dangers are manifold.

A few other injuries mentioned in the lawsuits include:

The Drugwatch report also mentioned King, whose doctor had prescribed him this medicine for treating opioid use disorder. The lawsuit he filed later stated that neither his doctor nor he was adequately warned about the side effects of Suboxone.

Additionally, it is interesting to note that much before the recent Suboxone legal claims, Indivior and Reckitt Benckiser, its former parent company, had witnessed civil and criminal charges for faulty marketing claims.

Therefore, it is necessary for people who are affected by this medicine to contact a lawyer and seek fair compensation for their losses.

Suboxone Tooth Decay Affects Mental and Physical Health

There are Suboxone users who have to pay extra medical bills for dental issues. The former addicts share that many of them have worked hard to get over their addiction and ended up losing out on their dental health. It deeply affected their mental and physical health.

One Suboxone user, identified as D.S. complained about the marketing tactics of the company. It is rather sad that when people are in a challenging phase of their lives, worried about whether they will live or die, drugmakers promote Suboxone as a miracle medicine.

She continued to use this medication for years. If only knew the side effects, perhaps she wouldn’t have used it or chosen safer alternatives. She had good dental health and was proud of it. Currently, she is having to fight cavities and has also lost many teeth.

The entire experience has made her develop depression, and she finds it tough to socialize. That aside, she is very afraid of losing the remaining teeth she has. There are several other cases akin to D.S. that the plaintiff’s attorneys are still investigating and are mostly in the early stages.

Based on the statutes of limitations, any person who has been affected by this medication should get in touch with a lawyer to file a lawsuit and get their share of compensation.

Contact a Lawyer

Navigating the legal landscape is a challenge. There are corrupt middle-men who pose to be helpful but end up taking your money and time, yielding nothing. As a layperson, it’s natural for you not to be aware of this.

Hence, a lawyer is the correct person to determine whether you qualify for a lawsuit or not. Typically, you can use a free consultation and share your case details and sufferings for them to examine and decide on your eligibility.

Once you do, your lawyer will guide you through the legal process and develop a compelling case that will ensure you get the compensation you deserve.

The lawyer will also provide the required support and assistance that will help you stay strong. If you follow their guidance, your chances of getting compensated increases.

In conclusion, dental health is of utmost importance and should be looked after well. It is indeed sad when a person aims to treat their OUD and ends up hurting their dental health. Such has been the case for most Suboxone users.

If you have faced a similar predicament, you must seek both medical and legal aid and help raise awareness about this.

Health

How Cold Water Immersion Boosts Your Immune System

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How Cold Water Immersion Boosts Your Immune System

After a cold plunge, once the initial shock wears off, the respiratory system kick-starts a controlled hyperventilation response. Your breathing rate accelerates considerably, serving a few purposes.

First, the accelerated breath rate warms incoming air before it reaches the lungs. Second, deeper breathing aids with circulatory functions to supply the body with additional oxygen. Both responses help restore homeostasis – balance within the body’s systems.

Blood Vessel Constriction

The best cold plunge tubs are designed to trigger another involuntary reflex – surface blood vessels rapidly constrict, limiting blood flow to the extremities. This process minimizes heat loss by keeping warm blood closer to the vital organs.

The blood vessel walls close tightly thanks to tiny muscles inside the vessels responding to neurological cues. This targets circulation towards critical life-sustaining systems.

After exiting the cold water, the opposite effect ensues as vasodilation allows blood to flow back out to the skin and extremities. This reopening sequence doesn’t occur uniformly but follows a pattern known as the Lewis Hunting Reaction.

First, blood redirects to the subcutaneous tissues before perfusing back out to muscles and finally skin. This progression prevents blood pressure drops while restoring circulation to essential areas first.

The effect of this is a “pumping” action. This ultimately helps drain metabolic waste from tissues while shuttling oxygen, nutrients, and immune cells to areas of need. Enhanced circulation and lymphatic drainage represent two core benefits of cold water immersion. And both of these are great for the immune system.

Cold Thermogenesis and Immune System Activation

The cascade of physiological effects sparked by cold water exposure falls under an emerging scientific field called cold thermogenesis. As researchers continue uncovering mechanisms, we now understand how significantly cold stress alters human biology.

When it comes to immune function, several interrelated adaptations play the biggest roles.

Hormones and Immune Cells Spike During Cold Exposure

Just as exercise stresses the muscular system in positive ways, cold water creates a productive strain on metabolic and immune operations.

Research shows this acute stress response from cold exposure activates several types of immune cells, including:

  • Neutrophils – The rapid responders that perform emergency phagocytosis on pathogens.
  • Monocytes – The middle-stage tactical units that become macrophages in tissues.
  • Eosinophils – Infection-fighters that specialize against multicellular parasites.
  • Natural Killer Cells – The immune system’s special forces that target virus-infected and cancerous cells.

These crucial cells exhibit amplified activity for up to 24 hours after cold water immersion. At the same time, the stress hormone and neurotransmitter levels normalize back to baseline. This shows how brief intense cold therapy triggers a beneficial cellular response without chronic stress side effects.

The Adaptive Immune System Also Reaps Rewards

While the acute cold exposure response centers around the innate immune system, downstream adaptive benefits also emerge. Improved lymphatic flow likely helps remove antigenic debris, enabling better antigen presentation to T & B lymphocytes.

Enhanced leucocyte circulation also assists with tumor immunosurveillance and tissue repair activities.

Furthermore, adrenaline and noradrenaline assist lymphocyte proliferation directly. They upregulate IL-2 receptor signaling on T-cells while promoting differentiation and antibody production from B-cells. In simpler terms, this equates to stronger pathogen-specific responses along with elevated resistance to reinfection.

Additional Mechanisms That Reinforce Immune Defense

Beyond immune cell stimulation and circulatory improvements, cold water immersion enhances several other physiological realms connected to immune defense and general wellness.

Mitochondria Density Ramps Up

All cells require efficient mitochondria to generate adequate energy, but immune cells more than others. Phagocytosis and rapid cellular proliferation place heavy ATP demands on neutrophils, macrophages, and lymphocytes.

In response to frequent cold stress, mitochondria production expands inside most cells – a process called mitochondrial biogenesis. This equates to better energy availability alongside improved oxidative capacity.

Enhanced mitochondrial density also benefits the endothelium lining blood vessels. Superior generation of nitric oxide relaxes artery walls leading to better circulation. Bolstered vasodilation continues long after emerging from a cold plunge.

Chronic Inflammation Gets Quieted

Lingering internal inflammation degrades health in numerous ways by contributing to autoimmunity, ischemic damage, neurodegeneration, and metabolic disorders. As a natural anti-inflammatory stimulus, cold water immersion attenuates inflammatory cytokine signaling. It also stimulates the elevated circulation of anti-inflammatory resolvins.

Patients with autoimmune conditions consistently report symptomatic relief from incorporating cold thermogenesis into their treatment plan. Reduced inflammation correlates to less pain and stiffness for many.

Cold’s anti-inflammatory effects likely stem from improved vagal tone via more acetylcholine output. This nervous system activation seems to quiet pro-inflammatory immune responses.

Rising Antioxidant Status

Upon exiting a cold plunge, blood antioxidant levels spike noticeably from baseline. This likely results from the stimulation of Nrf2 transcription pathways.

Nrf2 signaling prompts cells to produce their own endogenous antioxidants. And the higher availability of antioxidants bolsters resilience against free radicals and oxidative stress – both linked to weakened immunity as we age.

Preparation Guidelines for Safe and Effective Cold Exposure

While scientific data continues mounting on the positive immune effects of cold water immersion, don’t overlook proper precautions and preparation. Without building sufficient cold adaptation, jumping straight into an icy plunge can prove miserable… or worse, dangerous if underlying health conditions exist.

Let’s examine some best practices when adopting cold water immersion for immunity:

Test For Cold Tolerance First

One easy assessment involves placing your hands, arms, or feet in cold tap water. Monitor skin temp, time length, and your perception of discomfort.

Gradually work towards 5-10 minutes in the cold tap water over several sessions. Pay attention to any limb discoloration or numbness lasting more than 5 minutes after removal. Nerve damage risk elevates when cold exposure lasts beyond skin tolerance.

Start With Brief Endurable Exposures

Once you have established a reasonable cold tolerance, start fuller body immersion with very short durations. Many coaches recommend 30-90 seconds for the first few full-body plunges. Expect an immediate “gasp reflex” and accelerated breathing for the first 15-30 seconds.

After your heart rate elevates, consciously lengthen your exhalations and engage your diaphragm. Focus on feeling the cold water while maintaining calm concentration, rather than resisting or dreading the experience.

Exposure times under 3 minutes rarely risk hypothermia, even for lean individuals. Safety remains the priority here. Only progress plunge length once adaptation occurs. Consistency matters more than duration when starting.

Allow Sufficient Recovery Between Hard Exposures

Just like exercise, cold exposures require more recovery time to reap benefits without cumulative stress. After an intense 3-5 minute plunge in near-freezing water, take off at least 48 hours before the next session. However, gentle 30-to 90-second plunges can be repeated daily for beginners.

During the post-exposure period, nutrients and activities that boost nitric oxide can help widen blood vessels. Light movement or exercise also aids the rewarming process through muscular thermogenesis. Just avoid hot showers or baths immediately after emerging from a cold plunge since rapid heating causes blood pressure spikes.

Determining Who Can Benefit Most from Cold Exposure Therapy

While nearly everyone can derive some physical or mental benefits from brief cold water immersion, certain populations stand to gain the most from incorporating the practice:

Athletes and Active Individuals

Both professional athletes and recreational exercisers can accelerate workout recovery using cold water therapy. The exposure elicits vasoconstriction and vasodilation effects that reduce exercise-induced inflammation in muscles and joints. Some evidence also suggests that cold thermogenesis extends endurance by increasing tissue oxygen efficiency.

By reducing soreness and fatigue build-up, cold exposure enables faster turnaround between intense training sessions. It also counteracts the temporary immune suppression that often follows heavy exertion cycles. Just beware of attempting too much cold exposure within 48 hours pre-competition since performance may decline.

Individuals With Autoimmune Conditions

While not an autoimmune cure, cold thermogenesis eases multiple burdensome symptoms for many chronic inflammatory conditions. The skin, joints, and digestive tract tend to exhibit the most profound improvements as cold tolerance gradually builds. Start extremely conservatively with any autoimmune diagnosis before evaluating the effects.

Of course, obtaining physician clearance remains necessary for those with secondary Raynaud’s phenomena or at higher hypothermia risk. But when adapted appropriately, the anti-inflammatory and endorphin-releasing attributes provide an inexpensive adjunct therapy. Always avoid skin exposure exceeding diagnosed cold sensitivity levels, however.

Patients Seeking Improved Mental Health

The nootropic and mood-elevating response from cold water immersion works wonders for anxious, depressed, and brain fog-ridden individuals. The stimulation mandates heightened focus on the present moment, flooding awareness with cold sensation input. This inherently pulls the mind from ruminative thought patterns.

Additionally, the catecholamine and endorphin release buoys the mood for those with situational or biochemical depressive drivers. Anecdotally, many controlled cold exposure enthusiasts report sustained improvements in baseline happiness due to boosted resiliency.

Just be sure to consult any prescribing psychiatrist before incorporating it into a treatment plan.

Key Precautions Before Attempting Cold Water Immersion

Because cold water immersion remains an intense stressor, individuals with certain cardiovascular conditions should exercise abundant caution or avoid the practice altogether after professional consultation:

  • Uncontrolled stage 2 hypertension or history of arrhythmias
  • Confirmed ischemic heart disease or angina
  • Recent heart attack or stroke history
  • Class 3 or 4 heart failure
  • Pregnancy (with exceptions under guidance)
  • Raynaud’s disease
  • History of cold urticaria response
  • Poor peripheral circulation disorders

Additionally, those struggling with eating disorders or body dysmorphia should take care when adopting cold exposure for health purposes. The hormetic stress can become counterproductive without addressing underlying psychological drivers first.

Seek assistance from mental health experts rather than attempting rigorous regimens alone.

Final Takeaways on Leveraging Cold Adaptation

When adapted gradually using precautions, cold water immersion has systemic benefits – rooted in biology. It represents a free (or low-cost) intervention that nearly everyone can tap into with reasonable consistency and patience.

Beyond the direct immune-boosting perks, embracing cold therapy promotes self-reliance and mental resilience. Therefore, if you are interested, start conservatively, listen to your body, and don’t attempt to “tough out” excessive lengths of time. Allow your physiology to adapt at its own pace.

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Health

How to Combat Loneliness With Thoughtful Gestures

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How to Combat Loneliness With Thoughtful Gestures

It’s tough to know the right thing to do when you have a friend or family member experiencing loneliness. Perhaps they lost a loved one or went through a breakup. Or maybe they recently moved to a new place and haven’t made friends yet.

Then again, they could be more introverted and prone to feelings of loneliness. In any event, you want to be there for them, but you just don’t know how. Here are some thoughtful gestures to try.

Send Gifts

Gift baskets are rarely a bad idea when it comes to any kind of pain, loss, suffering, or discomfort. Loneliness can lead to great sadness and even, over time, depression, which only feels more isolating.

Once you’re in that cycle, it’s hard to break free, and sometimes you need an outside force to shake you up. The arrival of a physical gift meant to be bright and cheery can be just that necessary force.

A gift basket is ideal for combating loneliness because it can be personalized to the tastes and interests of the recipient. You can build the basket yourself, taking the time to pick out items your loved one will appreciate.

If you don’t have time for that, many companies offer get well gift baskets that can be tailored to your needs. Either way, the arrival of this thoughtful gesture is sure to make anyone feel less alone.

Pick Up the Phone

It sounds crazy in this age of texts and emails, but a phone call can go a long way toward making a person feel loved. Part of feeling lonely includes a lack of love and comfort from others.

Many people who feel secure in their relationships can go days, weeks, and even months living by themselves and not needing the company of others. In contrast, those who don’t have those bonds, or who are new to independence, might suffer more.

You can help someone suffering in this way by picking up the phone. If you know your friend or family member is someone who doesn’t typically answer, text them in advance to let them know you want to talk.

Then, when you get them on the phone, have a conversation like you would if you were sitting together in a cafe. Don’t focus on the person’s loneliness unless they bring it up. Just gossip and share funny stories to lighten the mood and lift their spirits. 

Plan to Hang Out

Speaking of sitting together in a cafe, if you live close to the person, plan a hangout session! It might seem obvious, but so many people are so busy these days, so you sympathize with someone’s plight but you shrug off the actual solution.

You can combat loneliness by spending time together. Friendship and community are beneficial to your overall health, too, so you’re doing something good for both of you.

Ask your loved one what they would like to do and then plan accordingly. If they can’t answer that question, take the matter into your own hands. Schedule a morning walk, which will boost endorphins and make you both happier.

Plan a trip to a local cafe for coffee and pastries. Or just bring snacks, magazines, and desserts over to their house and crash on their couch watching reality TV together. The idea is to combat loneliness with togetherness.

Pay for a Class

Another option if you’re physically close to each other is to take a class together. Classes are typically community-based as the people involved have a shared interest. They’re a great way to bring people together, discuss the topic at hand, and foster new friendships.

It’s also just an opportunity to get out of your house and be around other people. You get bonus points if the class is yoga or some other form of exercise that will boost happiness chemicals in your brain.

Even if you’re not close to your friend or family member, you can pay for a class you know they would like. During one of your chatty phone calls, you can pick their brain about their interests.

In most cities, you can find classes for just about anything. Pottery, paint and sip, writing, and more are offered at community centers and local studios. Get your friend a pass for a few classes and then check in on how it’s going.

Respond

Finally, and perhaps most obviously, one of the best things you can do for a friend who’s struggling with loneliness is to respond. So many people are so caught up in their own lives that they often don’t pick up on the subtle distress signals others are sending.

It’s so easy to leave someone on “read” and not get back to them for days or weeks. Of course, it’s not personal, but it can be detrimental to their state of mind.

You don’t have to send back a book-length text. Just respond when you see the text with something like, “Hey! I’m super busy right now. Let’s plan a call/walk/coffee date for this weekend!” Let the person know you see them, you hear them, and you’re here for them.

Just that quick, 30-second text can keep someone from feeling like they’re alone in this big, busy world. Then, be sure to follow up.

Again, there’s no perfect way or right way to help someone combat loneliness. And you might be struggling with your issues, too, so don’t take this situation on as a burden. Instead, see reaching out, sending a gift basket, or planning a morning walk as beneficial to your health.

Community, friendship, and good deeds are all contributors to feeling better about your life in general. And you’ll be helping someone else out along the way.

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Beauty

Ultimate Guide for Taking Care of Your Skin

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Ultimate Guide for Taking Care of Your Skin

Taking care of your skin isn’t just about looking good in the mirror. It’s also about ensuring that your skin stays healthy and resilient. Your skin is your body’s largest organ, and it deserves adequate attention and care just like your other organs do.

Whether you’re aiming to improve your skin’s appearance, tackle specific issues, or maintain its health, in this article, we will guide you through the core essentials of skin care.

Build a simple skincare routine

A basic skincare routine would be divided into morning and night sections. Here’s a rough idea:

Morning Routine:

  1. Cleanser: A gentle cleanser suitable for your skin type will remove dirt and oil.
  2. Toner (optional): This will help balance the skin’s pH.
  3. Moisturizer: Prevents dryness by hydrating your skin.
  4. Sunscreen: You must apply it before heading out for protection against UV damage and premature aging.

Night Routine:

  1. Cleanser: Remove all the makeup, dirt, and impurities that accumulate throughout the day.
  2. Treatment products: Use serums or creams for issues like acne. For this, we highly recommend Retinol Instytutum serum.
  3. Moisturizer: Lock in some hydration to repair your skin overnight.

Stay hydrated and eat a balanced diet

Staying hydrated is more important than you think for glowing skin. Drink at least 8 glasses of water daily to keep your body and consequently your skin hydrated. Water aside, consume a diet rich in fruits, vegetables, whole grains, and healthy fats. Your diet should include foods rich in:

  • Vitamin C (e.g., oranges, strawberries): For skin brightening and collagen production.
  • Vitamin E (e.g., almonds, sunflower seeds): For protecting skin from oxidative stress.
  • Omega-3 Fatty Acids (e.g., salmon, flaxseeds): For keeping skin soft and reducing inflammation.

Do proper exfoliation

Exfoliation helps remove dead skin cells, which leaves your skin smoother and more radiant. However, over-exfoliation can cause irritation and cause more damage. If you havedry or sensitive skin, exfoliate 1-2 times a week with a mild exfoliant. For oily skin, go for 2-3 times a week while focusing on areas prone to blackheads and clogged pores.

Use dermatologically-approved serums and products

Investing in dermatologically approved skin serums and products can work wonders for your skincare routine. These serums are formulated in such a way that skin concerns like acne, dark spots, fine lines, and dryness can all be addressed. Some popular ingredients to look for in these serums include:

  • Hyaluronic Acid: Helps in intense hydration.
  • Niacinamide: Reduces inflammation and evens the skin tone.
  • Retinol: Acts as an anti-aging material and improves skin texture.
  • Vitamin C: Reduces pigmentation.

Avoid harmful habits

Certain habits can harm your skin over time, even if the harm is not immediately noticeable. These include:

  • Skipping sunscreen: UV exposure is the main cause of premature aging and skin cancer, so you should never forget to put on your sunscreen.
  • Touching your face: This is impulsive to many, but this simple action, when repeated, can transfer bacteria and dirt to your face. This in turn can cause breakouts.
  • Sleeping with makeup on: Doing this will clog your pores and prevent the skin from repairing overnight.
  • Smoking and excess Alcohol: Both dehydrate your skin and consequently speed up aging.

Adjust your skincare to your environment

Your environment plays a bigger role than you think in your skin’s health. If you live in a hot, humid climate, you should always use lightweight, oil-free products. But if you’re living in cold and dry climates, opt for heavier moisturizers to combat dryness. That aside, protect your skin from pollution by using antioxidant-rich products.

Prioritize rest and stress management

Your skin is a reflection of your overall health. Lack of sleep and high levels of stress can lead to dullness, breakouts, and premature aging. It might be hard, but always aim for at least 7-8 hours of quality sleep every night. Practice stress-reducing activities like yoga, meditation, or exercise.

Visit a Dermatologist When Needed

If you’re dealing with persistent skin issues like acne, eczema, or severe dryness, consult a dermatologist without much delay. Untreated skin issues only get worse over time. A professional can provide personalized advice and treatments to help you achieve healthier skin.

Achieving healthy skin involves a combination of a consistent routine, smart product choices, and good lifestyle habits. By following these tips and investing in quality, dermatologist-approved products, you will surely be able to maintain an ever-glowing look.

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